Why We Relapse: Post Acute Withdrawal Syndrome Explained

The symptoms of Post Acute Withdrawal Syndrome (PAWS) can cause a person in recovery from drugs or alcohol addiction to relapse. To help us understand PAWS and its connection with relapse, please find the following guest post by James F. Davis, CAS.

James Davis is a Board Certified Interventionist and an expert on Post Acute Withdrawal and the Kindling Effect.  He is also the founder of a rehab center in South Florida that focuses on PAWS treatment and is himself a recovering cocaine addict and alcoholic with more than 32 years of sobriety.  Davis also operates an extensive not-for-profit website dedicated entirely to sufferers of PAWS, PostAcuteWithdrawal.org

James Davis shares his expertise and knowledge about Post Acute Withdrawal Syndrome (PAWS).

James Davis shares his expertise and knowledge about Post Acute Withdrawal Syndrome (PAWS).

 

Why We Relapse: Post Acute Withdrawal Syndrome Explained by James F. Davis, CAS

If you’ve ever relapsed from drugs or alcohol, chances are that it was symptoms of Post Acute Withdrawal Syndrome that caused you to “fall off the wagon.” But chances are also great that throughout your course of addiction treatment, PAWS was never addressed. As a result, in your newly sober state you weren’t prepared to re-integrate with your community because you didn’t have the knowledge or the resources needed to properly manage PAWS symptoms and prevent relapse. Educating yourself in this regard could mean the difference between a successful recovery and a relapse episode that could cost you everything.

What is Post Acute Withdrawal Syndrome?

PAWS is a set of symptoms and impairments caused by prolonged substance abuse. These symptoms usually appear immediately after detoxification and last for less than one year for most people in recovery.

PAWS symptoms are largely the result of neurological and behavioral changes that occur when mind-altering substances are abused to the point of tolerance and physical/psychological dependence. According to Terence Gorski, a leading addiction expert and founder of the CENAPS approach to addiction treatment, PAWS is a long-term brain dysfunction that is largely reversible given sufficient time. (1)

Symptoms vary significantly from person to person and include sleeplessness, depression, headaches/migraines, tingling in the hands and feet, restless leg syndrome, irritability, mood swings, tinnitus, poor gross and/or fine motor skills, anxiety and other symptoms that can significantly impair a person’s ability to remain sober.

However, none of these symptoms are as persistent and compelling as the acute, illogical urge to use drugs or drink again despite severe consequences.

What Causes Post Acute Withdrawal Syndrome?

*Evolutionary Response

The human body is an astounding collection of evolutionary systems and adaptations. However, modern man has evolved scientifically, socially and philosophically much faster than natural evolution can account for. This means that sometimes, primordial, built-in evolutionary systems can backfire and cause significant personal and social disruptions.

In simple terms, the immediate and constant availability of drugs and alcohol was never factored into human evolution. Consequently, the brain still rewards and seeks to reinforce behaviors that “feel good” in an effort to goad us into repeating them; even if those behaviors negatively impact our health and social standing. This is because the brain and central nervous system interpret things that make us feel good as being necessary for survival. (2)

Drugs and alcohol make us “feel good” – albeit temporarily and at a huge cost – so the brain naturally wants us to repeat these behaviors. And repeat them, and repeat them. Unfortunately, science has not yet advanced sufficiently to “turn off” this evolutionary survival mechanism, but there are some treatments in development that may be close. For instance, some researchers believe they have developed a cure for meth addiction: http://safedrugdetox.org/is-there-a-cure-for-meth-addiction/.

*Conditioned Response

The case of Ivan Pavlov’s drooling dogs demonstrated that animals can be conditioned both psychologically and physiologically. (2) Pavlov was a brilliant Russian physiologist who earned a Nobel Prize for his work in 1904; a significant portion of which was based on research focused on dogs.

Pavlov initiated an audio or visual cue just prior to feeding the dogs used in his research. When applied consistently, this resulted in salivation – the dogs responded to the cue and food physiologically by drooling. However, with consistent application of this technique the dogs soon began to drool when the cue was initiated – even if food was not subsequently presented.

Pavlov called the behavior exhibited by the drooling dogs “conditioned reflex,” and his research has since taught us a great deal about human behavior. For instance, the same principles of conditioned reflex can be applied to PAWS.

Consider the cocaine user who follows a similar drug abuse routine. In time the routine becomes a series of “cues” that later – in sobriety – may act as a trigger that causes a relapse episode. Seeing an old drug-using friend, hearing a specific song, going to an environment associated with drugs or alcohol, smelling a scent that was often prominent while using drugs such as patchouli, butane, baking powder, etc; all of these are cues associated with the Conditioned Response to drug addiction.

Fortunately, conditioned response is mostly temporary. Considering that the original behaviors associated with substance abuse led to the conditioned response, there is hope for people in recovery in that new behaviors can be learned and practiced and thereby replace the old.

*Physiological/Neurological Response

Just as Pavlov was able to quantify conditioned reflex, PAWS can be measured through brain scans (3). The process of becoming addicted to a substance results in the disruption of important neurotransmitter systems throughout the human body, and this is clearly evident when viewing before-and-after brain scans of drugs users.

In simple terms, prolonged drug abuse changes the human brain.

Most of the changes occur at the neuronal level and in the central nervous system. Changes are often reversible in time, but it is unclear if the brain ever returns to its 100% original state.

Alterations, damage and change in neurons, neurotransmitters and nerve networks cause a reduced ability to manage stress of all types, resulting in many of the classic symptoms of PAWS. Additionally, neurons and other brain functions that were once suppressed through drug use may become overly excited or depressed, resulting in a number of uncomfortable physical symptoms such as headache, insomnia, poor motor skills (dry drunk) and tinnitus.

Treatment for Post Acute Withdrawal Syndrome

The science behind PAWS might cause some to feel hopeless, but there is much to be optimistic about, as PAWS can be managed, reduced and eliminated with a variety of different treatments. These treatments cover a diverse selection of therapies ranging from individual counseling to biofeedback therapy to massage, medication, acupuncture, diet & exercise, emotional intelligence coaching, music and many other methods of directly treating PAWS symptoms.

To learn more about treatment for PAWS, check back to BreakingTheCycles.com for the next installment in this series, which will expand in detail on the various treatment types available to people in recovery.

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Sources:

(1) Gorski, Terence T.  Best Practice Principles In The Treatment Of Substance Use Disorders  GORSKI-CENAPS Web Publications  05/08/2003  http://www.tgorski.com/clin_mod/best_practices/Gorski%20Best%20Practice%20Standards%20010508.htm

(2) Durrant R, Adamson S, Todd F, Sellman D.  Drug use and addiction: evolutionary perspective.  Aust N Z J Psychiatry. 2009 Nov;43(11):1049-56. doi: 10.3109/00048670903270449.  Institute of Criminology, School of Social and Cultural Studies, Victoria University of Wellington, Wellington, New Zealand  http://www.ncbi.nlm.nih.gov/pubmed/20001400

(3) Ivan Pavlov – Biographical  NobelPrize.org  [From Nobel Lectures, Physiology or Medicine 1901-1921, Elsevier Publishing Company, Amsterdam, 1967] As published on: http://www.nobelprize.org/nobel_prizes/medicine/laureates/1904/pavlov-bio.html

(4) Gorski, Terence T.  WHAT IS THE POST ACUTE WITHDRAWAL (PAW) SYNDROME?  Focus Treatment Centers 04/11/2013  http://focustreatmentcenters.com/what-is-the-post-acute-withdrawal-paw-syndrome/

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13 Comments

  1. Charles Lyell on July 3, 2013 at 7:40 am

    Thanks for featuring this informative and helpful information.

    • James F. Davis on July 3, 2013 at 1:46 pm

      Thanks Charles. The dialogue on your site about dopamine is pretty fascinating, although there are certainly other important neurotransmitters in play when it comes to substance abuse, addiction, and PAWS. Have you had much dialogue in this regard from your readers?

      James F. Davis

      • Charles Lyell on July 4, 2013 at 4:23 am

        James,

        Every once in a while I receive a mention about the different neurotransmitters responsible for behavior. My general response is that I’m fully aware of the interplay of multiple brain chemicals but decided to focus on dopamine to streamline explanations. (My contention is that it doesn’t matter if one chemical or a dozen are manipulating behavior, the results are the same = a lack of free will.)

        Now that researchers have established that dopamine is actually about expectations (wants), as opposed to rewards, relapse makes a lot more sense. Dopamine is the reason so many of us want things we don’t need, don’t enjoy, don’t even like, and know are harmful to our health and life.

        Decades ago I started dabbling with cocaine and noticed that I wanted more and more while enjoying the “high” less and less. The realization made it easy to stop wasting my time and money on an expensive white powder.

        I suspect that children who are neglected, abused, or traumatized in any way are often burdened with unmet needs = insatiable cravings that send them scrambling to maximize dopamine flow. The problem is (as you noted without mentioning dopamine) excessive dopamine flow destroys sensitive receptors, so that chasing dopamine turns into a futile cycle of trying to put out the pain of withdrawal.

        I’m on a one-man crusade to try to get researchers to look into the possibility that the most dangerous and destructive addicts are triggering excessive dopamine by scrambling to score Maslow’s psychological needs for safety/power, acceptance/approval/attention, esteem/status. It’s an uphill battle, but I’m in it for the long haul.

        Thanks again for a great article.

        Charles

        • James F. Davis on July 4, 2013 at 8:14 am

          Thanks Charles; you covered so much so well in your reply, there’s not much else to say! I too am pushing for more research in the field in the hopes that we can change the primary focus of treatment from “let’s get you clean” to “let’s keep you clean once you leave here.” Your work is critical in this regard considering that we need to teach people how to control those neurological impulses, and of course the only way to do this is through a sound foundation in addiction theory. Which means we need more research considering that current addiction theory is really only in its infancy. We have a lot to learn.

          Being that addiction has been a part of the human condition for thousands of years and affects nearly every family in this country, I personally believe this type of education should be a part of elementary school education, even as early as the 3rd and 4th grade.

          • Lisa Frederiksen on July 4, 2013 at 8:51 am

            I absolutely agree with both of you, Charles and James! Thanks so much for your comments.

  2. Bev on July 3, 2013 at 9:02 am

    All good information James. It reminds me of how powerful music or smell is. A particular song can bring back feelings or memories from decades before. A particular smell say of home baked bread brings us back to our mother’s kitchen and for a few seconds we’re transported back into time. I’m looking forward to your next post : D

  3. Carolyn Hughes on July 5, 2013 at 4:08 am

    A very interesting and informative article Lisa. I was thinking back to my own experience of 12 step rehab and the fact that there was no mention at all of how alcohol affects the brain. Yet reading this makes me realise that a knowledge of the changes in the brain could be so helpful in getting sober and staying sober.
    Thank you Lisa.

    • James F. Davis on July 6, 2013 at 1:13 pm

      Hi Carolyn;

      You are absolutely right; knowledge can change everything for addicts. Surprisingly, I think that many people have the same rehab experience that you did; no mentions of the critical theory behind addiction and relapse are provided at thousands of rehabs across the country and probably worldwide.

      The problem with the application of many 12 Step programs/rehabs is that it is often applied like religion: there’s little factual, tested background information given, and sponsors invariably preach action over study, reflection and research when all are equally important.

      But my argument is this: how can you know how to act without fully understanding what you’re acting against? These days most people agree that addiction is a disease, but most also know nothing of the science behind this disease.

      In all fairness, even professionals in the industry know little about addiction, and the primary goal here is to educate AND act.

      Out of curiosity, how long have you been clean, and do you experience PAWS symptoms? Thanks for sharing, Carolyn.

      James F. Davis

  4. Trancend on June 26, 2014 at 6:00 am

    32 Years!!!

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